Growth factors

This domain centres on the growth hormone axis: the signals between hypothalamus and pituitary and the growth factors that follow. It includes GHRH analogues such as CJC-1295 and sermorelin, and ghrelin receptor agonists (GHRPs) such as ipamorelin and hexarelin.

IGF-1 analogues (IGF-1 LR3, PEG-MGF) and proteins around myostatin and activin signalling, such as follistatin and ACE-031, also belong here. Research focuses on receptor selectivity, pulsatile release and signal transduction in cell and tissue models.